The Future of Cell Therapy Manufacturing

True Walk-Away End-to-End Automation

Without compromising on process flexibility or process control.

Industrial Robot
Executes 10+ software-defined manufacturing workflows by moving closed cartridges from one bioprocessing instrument to the next.
Integrated Cleanroom Environment
True HEPA filters and automated sterilization methods establish a cleanroom environment, allowing the solution to be deployed in lower class environments.
QC Instruments
Automated sampling and integrated QC instruments generate rich in-process data.
Bioprocessing Instruments
The instrument configuration is optimized to achieve throughput matching for our customer’s processes.
GMP
Automated Feedthrough
Load GMP-in-a-box cartridges into the automated feedthrough to start up to 10+ independent cell therapy manufacturing workflows.
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Scalable

Ability to run 10+ processes simultaneously enables high-throughput process development in a scale-down model and commercial manufacturing in a scale-out model.

 

Closed & Automated

True walk-away end-to-end automation in a closed system enables 70% cost reduction and 3-fold reduction in process failure rates.

 

Process Control & Flexibility

Modular hardware and powerful software allow our customers to design and execute the processes that define their products.

We Power the Future of Cell Therapy

Cellares brings a unique value proposition to its customers.

Meet Patient Demand

Scale out to tens of thousands of patient doses per year and provide access to life-saving cell therapies.

Lower Cost

Up to 70% lower manufacturing cost for most cell therapy workflows due to elimination of human labor and reduced cleanroom needs.

Accelerate Market Entry

Continuity of a single technology platform from preclinical to commercial stage accelerates market entry by 1-2 years.

Reduce Vein-to-Vein Time

End-to-end automation significantly reduces dwell time compared to manual methods which leads to shorter manufacturing processes.

Improve Process Control

Tight control over all process parameters results in highly reproducible manufacturing results.

Improve Robustness

Eliminating opportunities for operator error and contamination leads to a three-fold reduction in the risk of process failure.

We Power the Future of Cell Therapy

Cellares brings a unique value proposition to its customers.

Meet Patient Demand

Scale out to tens of thousands of patient doses per year and provide access to life-saving cell therapies.

Lower Cost

Up to 70% lower manufacturing cost for most cell therapy workflows due to elimination of human labor and reduced cleanroom needs.

Accelerate Market Entry

Continuity of a single technology platform from preclinical to commercial stage accelerates market entry by 1-2 years.

Reduce Vein-to-Vein Time

End-to-end automation significantly reduces dwell time compared to manual methods which leads to shorter manufacturing processes.

Improve Process Control

Tight control over all process parameters results in highly reproducible manufacturing results.

Improve Robustness

Eliminating opportunities for operator error and contamination leads to a three-fold reduction in the risk of process failure.

“Cell therapy manufacturing reimagined – advancing automation that focuses on robust and reproducible cell processes that can deliver real cost savings, efficiencies and true scalability.“

Timothy Moore

President & COO, PACT Pharma

Cellares Advisory Board Member

 

GMP-in-a-Box Cartridge

A closed and single-use cartridge made for automation supports all processing steps from loading the starting material to unloading a cell therapy product ready for infusion.

  • Enrichment
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  • Isolation
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  • Activation
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  • Gene Transfer
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  • Expansion
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  • Formulation

Supported Applications

80% of Cell Therapy Modalities*

Autologous & Allogeneic Approaches

Centralized & Decentralized Manufacturing

*Cellares Cell Shuttle supports: CAR-T, HSC, TCR, NK, TIL, Treg, γδ T cells

Cellares Software Platform

Modern and intuitive software solution for process design, execution, monitoring, and reporting.

Define custom cell therapy workflows with complete control over all process parameters.

Industrial scale manufacturing execution system and process monitoring solution.

Real time monitoring of in-process data and auto-generation of electronic batch records.

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Process Development

High-throughput process optimization studies enable better cell therapy products.

Sampling & Analytics

Automated sampling and QC integration enable deeper understanding and ultimately better cell therapy products.

Electronic Batch Records

Cellares’ software platform has the ability to auto-generate electronic batch records while complying with 21 CFR regulations.